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Related Experiment Videos

Initial subgingival colonization of 'pristine' pockets.

M Quirynen1, R Vogels, M Pauwels

  • 1Department of Periodontology, Oral Pathology and Maxillo-Facial Surgery, Faculty of Medicine, Catholic University of Leuven, Kapucijnenvoer 7, B-3000 Leuven, Belgium. Mark.Quirynen@med.kuleuven.ac.be

Journal of Dental Research
|March 26, 2005
PubMed
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The supragingival environment rapidly seeds pristine implant pockets with complex bacterial communities, including pathogens, within one week. This rapid subgingival colonization highlights the importance of the oral microbiome

Area of Science:

  • Microbiology
  • Periodontology
  • Dental Implantology

Background:

  • Periodontitis and peri-implantitis treatment aims to eliminate periopathogens.
  • Subgingival areas are recolonized by both beneficial and pathogenic bacteria post-therapy.
  • The dynamics of this recolonization, particularly the supragingival environment's role, remain unclear.

Purpose of the Study:

  • To investigate the early colonization dynamics of pristine subgingival pockets around dental implants.
  • To determine the time required for a complex subgingival microbiota to establish solely from the supragingival environment.

Main Methods:

  • Prospective, split-mouth study design involving 16 partially edentulous patients.
  • Collection of subgingival plaque samples from implant sites and adjacent teeth at 1, 2, and 4 weeks post-abutment connection.

Related Experiment Videos

  • Analysis using Checkerboard DNA-DNA hybridization and microbial culturing.

    • Main Results:

    • A complex subgingival microbiota, including pathogenic species, was established in pristine pockets within one week.
    • Bacterial counts showed minimal increase from week 1 to week 4.
    • The supragingival area served as the primary source for colonizing bacteria.

    Conclusions:

    • A complex subgingival microbiota can rapidly develop within one week, originating from the supragingival environment.
    • This rapid colonization occurs even in 'pristine' pockets created during implant surgery.
    • Findings offer insights into the early microbial dynamics following dental implant placement.