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Clinical characteristics and treatment of constrictive pericarditis in Taiwan
Robert Fu-Chean Chen1, Cha-Po Lai
1Department of Thoracic and Cardiovascular Surgery, Taipei Medical University Hospital and Wan-Fang Hospital, Taipei, Taiwan.
Insights
Pericardiectomy is the primary treatment for constrictive pericarditis. This study highlights bacterial infections, particularly tuberculosis, as a key cause in Taiwan, with median sternotomy proving an effective surgical approach.
Area of Science:
- Cardiology
- Thoracic Surgery
- Infectious Disease
Background:
- Constrictive pericarditis restricts heart diastolic filling.
- Pericardiectomy is the established treatment for this condition.
Purpose of the Study:
- To review clinical characteristics and treatment outcomes of constrictive pericarditis patients undergoing pericardiectomy.
- To identify major etiologies and evaluate surgical approaches.
Main Methods:
- Retrospective review of 23 patients who underwent pericardiectomy for constrictive pericarditis.
- Surgical approaches included left anterolateral thoracotomy with transsternal extension and median sternotomy.
Main Results:
- Overall mortality rate was 8.7% (2 deaths).
- Major etiologies included Mycobacterium tuberculosis (8 patients), streptococcus (2), strongyloidiasis (1), post-myocardial infarction (1), post-cardiac surgery (2), connective tissue disorders (3), and idiopathic (6).
- Median sternotomy was used in 20 patients.
Conclusions:
- Bacterial infections, especially Mycobacterium tuberculosis, are a significant cause of constrictive pericarditis in Taiwan.
- Median sternotomy is an effective surgical approach for pericardiectomy.
Background:
Constrictive pericarditis is an uncommon disease that prevents the normal diastolic filling of the heart and pericardiectomy is the only satisfactory treatment.
Methods And Results:
The clinical characteristics and treatment of patients who underwent pericardiectomy for constrictive pericarditis (n = 23) were reviewed. Surgery was performed via left anterolateral thoracotomy plus transsternal extension in 3 patients, and median sternotomy in 20 patients. There were 2 deaths, resulting in an overall mortality rate of 8.7%. Of the 23 patients, 8 had Mycobacterium tuberculosis (Tb) infection, 2 had streptococcus infection, 1 had strongyloidiasis (Strongyloides stercoralis) and 1 developed the condition after a myocardial infarction; 2 patients underwent pericardial substitute insertion as post-heart surgery, and 3 patients had connective tissue disorders; 6 patients had idiopathic disease.
Conclusion:
These results show that bacterial infection, especially Tb, is a major etiology of constrictive pericarditis in Taiwan and that median sternotomy is an excellent approach for exposing the heart for pericardiectomy.
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