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Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids
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Optimized DNA targeting using N,N-bis(2-pyridylmethyl)-beta-alanyl 2'-amino-LNA

B Ravindra Babu1, Patrick J Hrdlicka, Christine J McKenzie

  • 1Nucleic Acid Center, I Department of Chemistry, University of Southern Denmark, DK-5230, Odense M, Denmark.

Chemical Communications (Cambridge, England)
|March 26, 2005
PubMed

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Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
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Proofreading

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Errors During Replication are Corrected by the DNA Polymerase Enzyme