Related Experiment Video

Updated: Aug 18, 2026

Clinical Efficacy of Ultrasound-Assisted Scoliosis-Specific Exercise in Mild-Grade Adolescent Idiopathic Scoliosis
07:01

Clinical Efficacy of Ultrasound-Assisted Scoliosis-Specific Exercise in Mild-Grade Adolescent Idiopathic Scoliosis

Published on: December 2, 2025

Two siblings with familial idiopathic scoliosis with conjugate gaze palsy

Faruk Incecik1, Mürüvet Elkay, M Ozlem Hergüner

  • 1Department of Pediatrics, Mustafa Kemal University Medical Faculty, Adana, Turkey.

Journal of Child Neurology
|March 29, 2005
PubMed

Insights

Familial idiopathic scoliosis with conjugate gaze palsy is a rare genetic disorder. This study presents two siblings with this condition, detailing their clinical and laboratory findings.

Area of Science:

  • Genetics
  • Neurology
  • Orthopedics

Background:

  • Familial idiopathic scoliosis with conjugate gaze palsy is a rare autosomal recessive disorder.
  • It is characterized by progressive spinal curvature and congenital absence of horizontal eye movement.

Observation:

  • This article presents two siblings diagnosed with scoliosis and conjugate gaze palsy.
  • Clinical and laboratory findings for these siblings are detailed.

Findings:

  • The study focuses on the clinical presentation and laboratory results of siblings affected by this rare condition.
  • Detailed analysis of the familial idiopathic scoliosis with conjugate gaze palsy in the presented cases.

Implications:

  • This case report contributes to understanding the rare genetic disorder familial idiopathic scoliosis with conjugate gaze palsy.
  • Further research into the genetic basis and clinical management of this condition is warranted.

More Related Videos

Clinical Efficacy of an Innovative Multidimensional Traction Therapy in Moderate Adolescent Idiopathic Scoliosis07:12

Clinical Efficacy of an Innovative Multidimensional Traction Therapy in Moderate Adolescent Idiopathic Scoliosis

Published on: February 10, 2026

Related Concept Videos

Prosopagnosia01:24

Prosopagnosia

Prosopagnosia, also known as face blindness, is the inability to recognize faces. In severe cases, individuals with prosopagnosia may not recognize close family members, including parents and spouses, by their faces. For instance, someone with prosopagnosia might walk past their child in a crowd, only realizing their mistake upon noticing their child's distinctive backpack or favorite jacket. Prosopagnosia specifically impairs facial recognition, while the recognition of other objects or...
Sex-linked Disorders01:43

Sex-linked Disorders

Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.
Muscles of the Eye01:20

Muscles of the Eye

The muscles of the eye are sophisticated structures that control eye movement and focus, allowing for the precise and rapid adjustments necessary for vision. The human eye is controlled by ten muscles — six extraocular muscles, three intraocular muscles, and one primary eyelid retractor muscle.
Extraocular Muscles
The six extraocular muscles surround the eyeball and control its movements. They are responsible for a wide range of eye motions, including looking up, down, left, right, and rotating...
Sex Linked Disorders01:43

Sex Linked Disorders

Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.
Nondisjunction01:29

Nondisjunction

During meiosis, chromosomes occasionally separate improperly. This occurs due to failure of homologous chromosome separation during meiosis I or failed sister chromatid separation during meiosis II. In some species, notably plants, nondisjunction can result in an organism with an entire additional set of chromosomes, which is called polyploidy. In humans, nondisjunction can occur during male or female gametogenesis and the resulting gametes possess one too many or one too few chromosomes.
Nondisjunction01:29

Nondisjunction

During meiosis, chromosomes occasionally separate improperly. This occurs due to failure of homologous chromosome separation during meiosis I or failed sister chromatid separation during meiosis II. In some species, notably plants, nondisjunction can result in an organism with an entire additional set of chromosomes, which is called polyploidy. In humans, nondisjunction can occur during male or female gametogenesis and the resulting gametes possess one too many or one too few chromosomes.