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New laboratory methods to study tooth surface coverage and interproximal plaque control by dentifrice products
Tao Xu1, Susan M Herles, Virginia M Barnes
1Colgate-Palmolive Technology Center, Piscataway, NJ, USA. Tao_Xu@colpal.com
Summary
A new in vitro tooth model effectively assesses dentifrice coverage and interproximal plaque control. This model supports the evaluation of oral care products, demonstrating superior plaque reduction with specific formulations.
Area of Science:
- Oral hygiene research
- Dental materials science
- In vitro study design
Background:
- Evaluating dentifrice efficacy is crucial for oral health.
- Existing methods may not fully capture interproximal plaque control.
- A reliable in vitro model is needed for standardized testing.
Purpose of the Study:
- To develop and validate an in vitro tooth model.
- To assess dentifrice coverage on tooth surfaces.
- To measure the efficacy of dentifrices in controlling interproximal dental plaque.
Main Methods:
- Utilized extracted human posterior teeth mounted in acrylic.
- Employed digital photography for visual assessment of dentifrice coverage.
- Incubated teeth with saliva and oral bacteria, then assessed plaque post-brushing using a clinical index.
Main Results:
- Dentifrices covered approximately 70% of the facial tooth surface.
- Colgate Total 2 in 1 Toothpaste and Mouthwash (CTTM) showed higher lingual coverage than Colgate Regular dentifrice (CRD).
- CTTM and Colgate Total dentifrice (CTD) demonstrated superior interproximal plaque control compared to CRD.
Conclusions:
- The developed in vitro tooth model effectively visualizes dentifrice coverage.
- The model accurately assesses the potential of dentifrices for interproximal plaque control.
- This model provides controlled evidence to support clinical evaluations of oral care products.