Revascularization of the right coronary artery: grafting or percutaneous coronary intervention?
Pierre-Emmanuel Falcoz1, Sidney Chocron, Christine Binquet
1Department of Thoracic and Cardiovascular Surgery, Jean-Minjoz Hospital, Besançon, France. pierre-emmanuel.falcoz@wanadoo.fr
Insights
For patients with multivessel disease, arterial grafting of the right coronary artery (RCA) offers better outcomes than percutaneous coronary intervention. The right internal thoracic artery is the most effective conduit for surgical revascularization.
Area of Science:
- Cardiovascular Surgery
- Interventional Cardiology
- Decision Analysis in Medicine
Background:
- The optimal myocardial revascularization strategy for the right coronary artery (RCA) in patients with multivessel disease and chronic stable angina is debated.
- Comparison between hybrid strategies (left coronary bypass + RCA PCI) and exclusive surgical approaches is lacking.
- Identifying the best conduit for surgical RCA revascularization is crucial.
Purpose of the Study:
- To compare the effectiveness of hybrid revascularization versus exclusive surgical revascularization for the RCA.
- To determine the optimal conduit for surgical revascularization of the RCA.
- To evaluate the impact of graft patency on strategy selection.
Main Methods:
- Decision analysis modeling was employed to compare surgical grafting and percutaneous coronary intervention (PCI) for RCA revascularization.
- A comprehensive literature review identified key variables for each strategy.
- Sensitivity analysis was performed to identify critical factors and threshold values.
Main Results:
- Arterial grafting of the RCA demonstrated superior effectiveness compared to PCI (6% higher) and saphenous vein grafting (7% higher).
- The right internal thoracic artery (RITA) was identified as the most effective arterial conduit.
- Surgery is favored when the 1-year arterial graft patency rate exceeds 80%.
Conclusions:
- Arterial grafting of the RCA provides better outcomes than percutaneous coronary intervention.
- The right internal thoracic artery is the preferred conduit for surgical RCA revascularization.
- Graft patency rates significantly influence the choice of revascularization strategy.
Background:
The choice of myocardial revascularization strategy for the right coronary artery (RCA) in patients with multivessel disease and chronic stable angina remains controversial. Our aim was to determine the better strategy-hybrid, combining bypass of the left coronary network and percutaneous coronary intervention of the RCA, or exclusively surgical-and if the latter, the best conduit.
Methods:
We used decision analysis, a modeling technique, to compare two RCA revascularization strategies: surgical grafting and percutaneous coronary intervention. A review of the English language literature determined the variables for each strategy. All possible outcomes of each strategy were analyzed to determine the baseline strategy yielding the highest expected effectiveness. Sensitivity analysis determined the most relevant elements in the model and indicated threshold values.
Results:
Arterial grafting of the RCA led to the highest expected effectiveness, respectively 6% and 7% higher than that of percutaneous coronary intervention and the saphenous graft procedure. Of the arteries available-the radial, right gastroepiploic, and right internal thoracic artery-the most effective was the right internal thoracic artery, pedicled for the proximal part of the RCA and free connected as a Y or a T to the pedicled left internal thoracic artery for the distal part of the RCA. Sensitivity analysis showed surgery to be the appropriate strategy when the expected 1-year patency rate of the arterial graft exceeded 80%.
Conclusions:
This analysis shows arterial grafting of the RCA to have better outcomes than percutaneous coronary intervention, and the right internal thoracic artery to be the best conduit.
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