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Functional heme oxygenase-1 promoter polymorphism in relation to heart failure and cardiac transplantation
Cecile T J Holweg1, Aggie H M M Balk, André G Uitterlinden
1Department of Internal Medicine, University Medical Center Rotterdam, Rotterdam, The Netherlands. cholweg@cvmed.stanford.edu
Abstract:
We investigated the functional promoter repeat polymorphism (GT)(n) in the oxidative stress-induced enzyme heme oxygenase-1 in relation to heart failure and complications after transplantation. No influence of the polymorphism on the development of heart failure, graft survival, acute rejection, or transplant atherosclerosis was found.
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