Neoplasms of the renal medulla: radiologic-pathologic correlation

Tumors of the renal medulla cover a wide spectrum, with characteristic histomorphology and variable biologic profiles. Renal medullary tumors can be categorized into benign and malignant neoplasms based on histologic features and clinico-biologic behavior. They can be further classified into pediatric and adult tumors based on the patient age group. When small, renal medullary tumors may be differentiated from the more common renal adenocarcinomas by their central location and certain demographic characteristics. Although most large malignant medullary tumors demonstrate imaging findings that are indistinguishable from those of other renal malignancies, some tumors demonstrate imaging findings that may suggest a specific diagnosis.