Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Chitosan-based particles as controlled drug delivery systems.

M Prabaharan1, J F Mano

  • 1Biomaterials, Biodegradables and Biomimetics, Department of Polymer Engineering, University of Minho, Guimaraes, Portugal. prabaharan@dep.uminho.pt

Drug Delivery
|April 2, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Preparation and characterization of chitosan/carboxymethyl pullulan/bioglass composite films for wound healing.

Journal of biomaterials applications·2021
Same author

Graphene oxide-reinforced pectin/chitosan polyelectrolyte complex scaffolds.

Journal of biomaterials science. Polymer edition·2021
Same author

Platelet lysates-based hydrogels incorporating bioactive mesoporous silica nanoparticles for stem cell osteogenic differentiation.

Materials today. Bio·2021
Same author

Modeling of Cell-Mediated Self-Assembled Colloidal Scaffolds.

ACS applied materials & interfaces·2020
Same author

Preparation and characterization of chitosan/pectin/ZnO porous films for wound healing.

International journal of biological macromolecules·2020
Same author

Free and copolymerized γ-cyclodextrins regulate the performance of dexamethasone-loaded dextran microspheres for bone regeneration.

Journal of materials chemistry. B·2020

Chitosan, a natural polymer, shows promise for drug and gene delivery. Its unique properties enable effective transport of bioactive molecules via colloidal structures and liposome coatings.

Area of Science:

  • Biomaterials Science
  • Polymer Chemistry
  • Drug Delivery Systems

Background:

  • Chitosan, derived from chitin, offers biocompatibility and biodegradability.
  • Its properties make it suitable for advanced drug and gene delivery applications.

Purpose of the Study:

  • To review methods for associating bioactive molecules with chitosan.
  • To analyze chitosan's efficacy in enhancing molecular transport across biological barriers.
  • To examine chitosan's role in nonviral gene delivery.

Main Methods:

  • Review of literature on chitosan-based colloidal structures for drug delivery.
  • Analysis of chemical modification and crosslinking techniques for chitosan.
  • Examination of chitosan's application in liposome formulations and gene delivery.

Related Experiment Videos

Main Results:

  • Chitosan effectively entraps bioactive molecules via chemical/ionic crosslinking and complexation.
  • Chemically modified chitosan aids in controlled drug release.
  • Chitosan enhances molecule transport across mucosae and epithelia.
  • Chitosan shows potential as a nonviral gene delivery agent.

Conclusions:

  • Chitosan and its derivatives are effective for controlled drug delivery.
  • Chitosan is a promising material for nonviral gene delivery applications.