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Updated: Aug 18, 2026

Event-related Potentials During Target-response Tasks to Study Cognitive Processes of Upper Limb Use in Children with Unilateral Cerebral Palsy
Published on: January 11, 2016
[Contingent negative variation (CNV) as presaccadic potential]
1Department of Ophthalmology, School of Medicine, Keio University, Shinjuku-ku, Japan.
Abstract:
By recording contingent negative variation (CNV) with saccade as the response, EEGs were recorded before, during and after saccade. Light-emitting diodes (LEDs) were used as the warning stimulus (S1) and the imperative stimulus (S2), and a different electrode was placed on Cz according to the international 10-20 system. Evoked potentials were amplified by a D.C. amplifier and 16 responses were averaged. EOGs were recorded simultaneously. There were no remarkable changes in CNV according to the S1-S2 interval or angle of saccade. A positive wave of approximately 10 microV was observed prior to saccade, and was not believed to be the influence of either EOG or blinking. This positive wave may be similar to the spike potential in presaccadic potentials or may be a component of postimperative negative variation (PINV).

