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Processing of Bronchoalveolar Lavage Fluid and Matched Blood for Alveolar Macrophage and CD4+ T-cell Immunophenotyping and HIV Reservoir Assessment
Published on: June 23, 2019
Ocular tuberculosis in acquired immune deficiency syndrome (AIDS)
Salil Mehta1, Ishwarprasad S Gilada
1Lilavati Hospital and Research Center, Mumbai, India. doc@retinaconsultant.com
Aim:
To determine the prevalence and clinical features of ocular tuberculosis in patients with the acquired immune deficiency syndrome (AIDS).
Design:
Prospective cross-sectional study.
Methods:
Detailed history and ocular examination of 46 patients (92 eyes) in the outpatient department of an AIDS clinic.
Results:
Seventeen of 46 (36.9%) patients had clinical and radiological evidence of pulmonary tuberculosis. Of these, four (23.5%) showed findings consistent with ocular tuberculosis. Lesions included tubercles (1 eye of 3 patients) and chorioretinitis (1 eye of 1 patient). Commonly, these patients had evidence of abdominal tuberculosis. Hemorrhages, cotton-wool spots, herpes zoster ophthalmicus (HZO), cytomegalovirus retinitis (CMVR), and disc edema were other non-tubercular AIDS-related lesions and were seen in seven of the remaining 42 patients (16.2%).
Conclusion:
Ocular tuberculosis was a common finding in this study and was found in profoundly immunocompromised patients with disseminated tuberculosis. Diagnosis of ocular tuberculosis may help reduce HIV/tuberculosis co-infection mortality.
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