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Related Experiment Videos

Glioblastoma multiforme in pregnancy.

Andrew P Mackenzie1, Gary Levine, David Garry

  • 1Department of Obstetrics and Gynecology, Winthrop University Hospital, Mineola, New York 11501, USA.

The Journal of Maternal-Fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
|April 5, 2005
PubMed
Summary

Brain tumors during pregnancy are rare. A pregnant patient with a glioblastoma multiforme presented with neurological symptoms, underwent cesarean delivery and surgery, but unfortunately passed away nine months later.

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Area of Science:

  • Neurology
  • Obstetrics
  • Oncology

Background:

  • Brain tumors complicating pregnancy are infrequent.
  • Glioblastoma multiforme is an aggressive primary brain tumor.

Observation:

  • A 48-year-old pregnant patient at 36 weeks gestation presented with acute neurological deficits including right-sided weakness, facial droop, and gait instability.
  • Brain imaging identified a left parietal lesion causing mass effect on the lateral ventricle.

Findings:

  • The patient underwent emergent cesarean delivery followed by craniotomy for glioblastoma multiforme resection.
  • Despite adjuvant radiation and chemotherapy, the patient had a poor prognosis, succumbing to the disease nine months post-operatively.

Implications:

Related Experiment Videos

  • This case highlights the critical presentation of glioblastoma multiforme during pregnancy, necessitating a multidisciplinary approach.
  • Prompt diagnosis and management, including delivery and surgical intervention, are crucial for maternal outcomes in such rare obstetric emergencies.