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Updated: Aug 18, 2026

Determining Basal Energy Expenditure and the Capacity of Thermogenic Adipocytes to Expend Energy in Obese Mice
Published on: November 11, 2021
Metabolically active components of fat free mass (FFM) and resting energy expenditure (REE) in humans
Manfred J Müller1, Anja Bosy-Westphal, Doris Kutzner
1Institut für Humanernährung und Lebensmittelkunde, Agrar- und Ernährungswissenschaftliche Fakultät, Christian-Albrechts-Universität zu Kiel, Germany. mmueller@nutrfoodsc.uni-kiel.de
Abstract:
Magnetic resonance imaging (MRI) can be used to assess metabolically active components of FFM. MRI-derived organ mass (OM) explains part of the interindividual variance in REE. It may also add to our understanding of malnutrition- and obesity-related variance in REE. There is need for (i) standardisation of MRI technology in body composition research, (ii) reference data on detailed body composition including also more recent autopsy data, (iii) reducing the number of assumptions in model-based predictions and (iv) a combination of imaging technologies with in vivo measurements of individual OM respiration (e.g. by positron emission tomography).
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