Multicystic dysplastic kidney: conservative management and follow-up
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Published on: June 23, 2015
Said Al-Ghwery1, Abdulrahman Al-Asmari
1Department of Pediatrics, Riyadh Military Hospital, Riyadh, Saudi Arabia.
Insights
Multicystic dysplastic kidney (MCDK) disease in children often resolves spontaneously. Conservative management showed that affected kidneys tend to involute over time without complications.
Area of Science:
- Pediatric Nephrology
- Urology
- Medical Imaging
Background:
- Multicystic dysplastic kidney (MCDK) is a congenital condition.
- Conservative management is a key approach for MCDK.
- Understanding the natural history of MCDK is crucial for clinical practice.
Purpose of the Study:
- To evaluate the outcomes of conservative management in children diagnosed with MCDK.
- To assess the natural progression and involution patterns of MCDK lesions.
- To determine the complication rate associated with conservative MCDK management.
Main Methods:
- Prospective follow-up of 35 children diagnosed with MCDK between 1992 and 2003.
- Utilized static scintigraphy with dimercaptosuccinic acid and micturating cystourethrogram for initial assessment.
- Regular ultrasonography (US) examinations conducted every 3 months, then annually, for monitoring.
Main Results:
- Partial involution observed in 48.6% and complete involution in 37.1% of cases.
- Mean age at complete or partial involution was 43.7 months.
- No complications like hypertension or tumors were reported; all children maintained normal growth and development.
Conclusions:
- MCDK lesions are frequently benign and show a tendency for spontaneous involution.
- Conservative management appears safe and effective, leading to favorable outcomes.
- Long-term monitoring confirms the self-limiting nature of many MCDK cases.
Abstract:
This study reports our experience in the conservative management of multicystic dysplastic kidney (MCDK) disease. Between 1992 and 2003, 35 children, 18 male (51.4%) and 17 female (48.6%), were diagnosed with MCDK and prospectively followed at the Riyadh Armed Forces Hospital. Static scintigraphy with dimercaptosuccinic acid and micturating cystourethrogram were performed in all patients. Ultrasonography (US) examinations were conducted every 3 months, and then annually. Mean age at diagnosis during the postnatal period was 2.4 days. Median follow-up time was 33.75 months. Follow-up US examinations showed partial involution in 17 (48.6%), complete involution in 13 (37.1%), and 5 (14.3%) showed an unchanged size without any pathological manifestations. The mean age at complete or partial involution of the lesion was 43.7 months. No child developed complications such as hypertension or tumors, and all maintained normal growth and development. In conclusion, MCDK lesions are often benign, and the affected kidneys tend to show involution with time.
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