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Updated: Aug 18, 2026

Transport Properties of Ibuprofen Encapsulated in Cyclodextrin Nanosponge Hydrogels: A Proton HR-MAS NMR Spectroscopy Study
Published on: August 15, 2016
[Study on preparation of the inclusion compound of curcumin with beta-cyclodextrin]
Gang Han1, Jianhua Xu, Weina Li
1Pharmaceutical Department, North China Coal Mine Medical College, Tangshan.
Objective:
The inclusion compound of curcumin with, beta-CD was preparated to increase the solubility and bioavaliability of curcumin.
Methods:
Prepare inclusion compound was studied with orthogonal design. The inclusion compound was verified with fluorometry, TLC, and phase solubility.
Result:
The best way to prepare inclusion compound are as follows: the molar ratio between curcumin and, beta-CD is 1:1, temperture is 40 degrees C, reaction time is 2 h.
Conclusion:
Solubility of inclusion compound is 10 times than curcumin.
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