Related Experiment Video
Updated: Aug 18, 2026

Intracameral Injection in Rats with Low Risk of Adverse Effects
Published on: May 31, 2024
Retained antibiotic ophthalmic ointment on an intraocular lens 34 months after sutureless cataract surgery
Ko-Hua Chen1, Shan-Yang Lin, Mei-Jane Li
1Department of Ophthalmology, Taipei Veterans General Hospital and National Yang-Ming University, Taipei, Taiwan.
Purpose:
To quickly examine the long-term retained oily-like material on the intraocular lens (IOL) of a sutureless cataract surgical patient.
Design:
Observational case report.
Methods:
Fourier transform infrared (FT-IR) and confocal Raman microspectroscopies were used to identify the deposited materials on explanted IOL.
Results:
A 70-year-old man underwent a sutureless cataract surgery for his right eye. Garamycin ophthalmic ointment was postoperatively applied on the conjunctival fornix. His vision was improved to 20/25 after surgery but declined gradually to 20/400 half a year later. An oily-like hump on the anterior surface of IOL was found and he underwent IOL exchange after approximately 3 years. The oily-like material was identified by using FT-IR and Raman microspectroscopies to be garamycin ophthalmic ointment.
Conclusions:
Both FT-IR and Raman microspectroscopies can easily examine the retained antibiotic ophthalmic ointment on the IOL. Direct access of ophthalmic ointment into ocular anterior chamber through the sutureless incision is a potential risk.
Related Concept Videos
Ophthalmic Drug Delivery Systems
Angle Closure Glaucoma: Treatment
Glaucoma: Overview
Microbiome of the Eye
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
