Stretch-induced cell proliferation is mediated by FAK-MAPK pathway

Ju Guang Wang1, Motoi Miyazu, Peng Xiang

  • 1Research Center of Stem Cells Biology and Tissue Engineering, Sun Yat-Sen University, 74 Zhong Shan Road 2, Guang Zhou 510080, China. Juguangw@hotmail.com

Life Sciences
|April 6, 2005
PubMed
Summary

Mechanical stretch triggers fibroblast proliferation through focal adhesion kinase (FAK) and mitogen-activated protein kinase (MAPK) pathways. This study confirms FAK and MAPK activation are crucial for stretch-induced cell growth.

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