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State of the Art Cranial Ultrasound Imaging in Neonates
10:02

State of the Art Cranial Ultrasound Imaging in Neonates

Published on: February 2, 2015

Magnetic resonance and ultrasound brain imaging in preterm infants

T Michael O'Shea1, Serena J Counsell, Dorothee B Bartels

  • 1Department of Pediatrics, Wake Forest University School of Medicine, Medical Center Blvd, Winston-Salem, NC 27157, USA. moshea@wfubmc.edu

Early Human Development
|April 9, 2005
PubMed

Insights

Cranial ultrasonography and magnetic resonance imaging are used to assess brain injury in preterm infants. This review compares their findings with histology and neurodevelopmental outcomes.

Area of Science:

  • Neonatal neurology
  • Pediatric neuroimaging
  • Developmental neuroscience

Background:

  • Cranial ultrasonography (US) has a long history in evaluating brain injury in preterm neonates.
  • Magnetic resonance imaging (MRI) is increasingly utilized for assessing brain development and pathology in this population.
  • Histology and neurodevelopmental outcomes serve as critical benchmarks for imaging accuracy.

Purpose of the Study:

  • To review the concordance of cranial ultrasonography and MRI findings with histological data.
  • To evaluate the correlation between neuroimaging findings and long-term neurodevelopmental outcomes in preterm infants.
  • To compare the diagnostic capabilities of ultrasound versus MRI in preterm neonates.

Main Methods:

  • Systematic review of studies comparing cranial ultrasonography and MRI in preterm neonates.
  • Analysis of studies correlating imaging findings with post-mortem histology.
  • Examination of research linking neuroimaging results to neurodevelopmental assessments.

Main Results:

  • The review synthesizes evidence on the agreement between US and MRI findings and histological correlates.
  • It assesses how well each modality predicts neurodevelopmental outcomes.
  • Comparative data on the strengths and limitations of US and MRI are discussed.

Conclusions:

  • Both cranial ultrasonography and MRI provide valuable insights into brain injury and development in preterm infants.
  • Understanding the concordance with histology and neurodevelopmental outcomes is crucial for accurate diagnosis and prognosis.
  • The choice of imaging modality may depend on the specific clinical question and available resources.

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