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Published on: July 5, 2021
An autopsy case of Brugada syndrome with significant lesions in the sinus node
Shin-ichiro Morimoto1, Akihisa Uemura, Hitoshi Hishida
1Division of Cardiology, Department of Internal Medicine, Fujita Health University School of Medicine, Toyoake, Japan. morimoto@fujita-hu.ac.jp
Abstract:
A 30-year-old man with Brugada syndrome died suddenly. The heart weighed 380 g. The left ventricular wall showed mild thickening, and marked fatty tissue deposition was noted in the right ventricular outflow tract. Neither ventricle was enlarged. Contraction band necrosis was diffuse in both ventricles. In the ventricles no cardiac muscle cell hypertrophy or atrophy, or significant interstitial fibrosis was observed. In the sinus node the number of nodal cells was reduced by half, with fatty tissue and fibrosis prominent. But no lesions were evident in the right bundle branch.
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