Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Progressive and nonresolving pneumonia.

Donald E Low1, Tony Mazzulli, Tom Marrie

  • 1Department of Microbiology, Toronto Medical Laboratories and Mount Sinai Hospital, Ontario, Canada. dlow@mtsinai.on.ca

Current Opinion in Pulmonary Medicine
|April 9, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Incidence of colonization and infection with carbapenemase-producing Enterobacterales in Toronto and Peel Region, Ontario, 2007-2024.

Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada·2026
Same author

Optimizing Hepatitis C Virus Antibody Testing Strategy and Setting: Results From a Large Real-World Screening Program.

Open forum infectious diseases·2026
Same author

Findings from comprehensive genome sequencing in the Canadian population: Results from the GENCOV Study.

Genetics in medicine open·2026
Same author

International multisite implementation of distributed cell-free protein biomanufacturing to advance health and research equity.

Science advances·2026
Same author

Phosphorylated lantibiotics-producing commensals integrate into the human oral microbiome to suppress pathogens and promote microbiome homeostasis.

NPJ biofilms and microbiomes·2026
Same author

Early COVID-19 and Severity of Subsequent Omicron Infection in Ontario Canada.

Influenza and other respiratory viruses·2026
Same journal

Nonsteroid treatment options in (pulmonary) sarcoidosis. When to consider and why?

Current opinion in pulmonary medicine·2026
Same journal

Multidisciplinary approach in cardiac sarcoidosis: to biopsy or not?

Current opinion in pulmonary medicine·2026
Same journal

Low diffusion capacity in pulmonary hypertension.

Current opinion in pulmonary medicine·2026
Same journal

Toward precision imaging in interstitial lung disease: advances in quantitative imaging and artificial intelligence.

Current opinion in pulmonary medicine·2026
Same journal

Oxygen therapy in interstitial lung disease - navigating benefit and burden.

Current opinion in pulmonary medicine·2026
Same journal

Preclinical and clinical advances in pulmonary hypertension associated with systemic sclerosis.

Current opinion in pulmonary medicine·2026
See all related articles

Identifying patients with progressive or nonresolving community-acquired pneumonia early is crucial for reducing morbidity and mortality. This review highlights updated clinical, laboratory, and radiologic findings to aid in early risk identification and treatment.

Area of Science:

  • Pulmonology
  • Infectious Diseases
  • Critical Care Medicine

Background:

  • Community-acquired pneumonia (CAP) can lead to severe morbidity and mortality, particularly when progressive or nonresolving.
  • Early identification of at-risk patients is essential for timely and effective therapeutic interventions.

Purpose of the Study:

  • To summarize recent advancements in identifying patients at risk for progressive or nonresolving CAP.
  • To review emerging infectious causes and novel treatment strategies for complicated pneumonia.

Main Methods:

  • Literature review of recent clinical, laboratory, and radiologic findings.
  • Analysis of studies on treatment failure causes, including pathogens and antimicrobial discordance.
  • Inclusion of newly recognized infectious diseases and their impact on pneumonia progression.

Related Experiment Videos

Main Results:

  • Identified clinical, laboratory, and radiologic markers for predicting pneumonia complications.
  • Highlighted pathogens and discordant antimicrobial therapy as key factors in treatment failure.
  • Discussed emerging infectious diseases like SARS, avian influenza, and MRSA.
  • Presented promising treatments for overwhelming immune responses, such as activated protein C and IVIG.

Conclusions:

  • Progressive and nonresolving pneumonia signify treatment failure due to various factors, including incorrect initial therapy, noninfectious causes, or overwhelming immune responses.
  • Crucial to identify patients with nonresponding pneumonia and those at risk for progressive disease for appropriate management.