Related Experiment Video
Updated: Aug 18, 2026

Longitudinal Intravital Microscopy Using a Mammary Imaging Window with Replaceable Lid
Published on: January 20, 2022
Womb with a view
Edgar V Mocanu1, Salem Adala, John J O'Leary
1Human Assisted Reproduction Ireland, Rotunda Hospital, Dublin 1, Ireland. emocanu@rcsi.ie
Abstract:
Zygote transfer is a significant limiting factor in pregnancy rates after Assisted Reproductive Technology (ART) treatment. Adequate technique appraisal should be a high priority task for any medical facility that offers this treatment. Although many clinicians have extensive personal experience, it is difficult for trainees to understand the anatomical and mechanical process of safe and adequate placing of zygotes in the uterine cavity. Ultimately, even with ultrasound help, it is a "blind procedure". The experimental module described here allows for direct visualisation of the mechanical passage of a catheter through the cervix and final placement of the tip in relation to the intravaginal visible part of the catheter. It has worldwide practical applicability for trainees and experienced clinicians accompanying the theory and allowing adequate training and retraining of all staff performing zygote transfers.
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