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Updated: Aug 18, 2026

Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability
Published on: August 6, 2021
[Bilateral central retinal vein occlusion associated with blood hyperviscosity syndrome--case report]
John Helal1, Fernando Korn Malerbi, Roberto Melaragno Filho
1Clínica Oftalmológica, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo.
Abstract:
The authors report the case of a 16-year-old male patient who presented with blurred vision and bilateral optic disc edema, then developing bilateral central retinal vein occlusion. On laboratory work-up, he was found to have multiple myeloma IgA along with hyperviscosity syndrome, which led to the ophthalmological features. After proper treatment, the patient recovered visual acuity and normalized his eye fundus changes. Bilateral central retinal vein occlusion finding may yield the diagnosis of major systemic diseases. Fundoscopic features may serve as parameters on treatment evaluation.
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