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[Tropical sprue revealed by severe anemia in a woman from Guadeloupe]

Y Hutin1, C Eugène

  • 1Unité de Gastroentérologie, Centre Hospitalier Intercommunal, Poissy.

Gastroenterologie Clinique Et Biologique
|January 1, 1992
PubMed

The case of a young woman from Guadeloupe developing severe megaloblastic anemia is reported. She presented with fever and hemolysis (she had heterozygotic beta-thalassemia) after a six month history of diarrhea. She was shown to have folate deficiency, steatorrhea, vitamin K and B12 malabsorption. She responded well to intravenous folinic acid and tetracyclines. Diagnosis was based on the following criteria: a) no other cause of malabsorption was found despite a comprehensive inquiry, b) the pattern of the illness corresponded to the definition of disease. Three particular aspects are outlined: the acute onset, malabsorption of vitamin B12 requiring prolonged and combined treatment, and the unusual place in which the disease was contracted.

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