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Cadaver testing to validate design criteria of an adult intraosseous infusion system
David L Johnson1, Judy Findlay, Andrew J Macnab
1Pyng Medical Corp., Richmond, British Columbia, V6V 2E9, Canada.
Introduction:
The FAST 1 intraosseous (IO) infusion system was designed to deliver fluids and medications into the adult sternum in the prehospital and battlefield environments.
Objective:
To test the prototype in 106 cadavers and excised sterna and compare it with other IO devices.
Results:
The insertion force was similar to that of other IO devices (mean, 8.5 kg; range, 2.3-19.6 kg). In 39 of 39 trials, the depth-control mechanism inserted the portal within 1.0 mm of a predetermined distance below the anterior surface of the cortical bone. If misplaced, underpenetration was more likely than overpenetration (mean displacement, -0.3 mm; SD, 0.5 mm). After release, the portal could not be advanced further into the manubrium. Marrow was accessed in 75 of 77 trials. Mean flow rates were 109 mL/min for normal saline solution and 102 mL/min for hypertonic saline/dextran, similar to the Cook Sur-Fast device.
Conclusion:
The cadaver and bench tests demonstrated the reliability and safety of the FAST 1 system at the design/prototype stage.
