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Cerebral infarction in diabetes: clinical pattern, stroke subtypes, and predictors of in-hospital mortality

Adrià Arboix1, Antoni Rivas, Luis García-Eroles

  • 1Cerebrovascular Division, Department of Neurology, Hospital del Sagrat Cor, Universitat de Barcelona, Viladomat 288, E-08029 Barcelona, Spain. aarboix@hscor.com

BMC Neurology
|April 19, 2005
PubMed

Insights

Diabetic patients with ischemic stroke show distinct patterns, including more atherothrombotic and lacunar strokes. Early clinical factors predict in-hospital mortality, aiding prognosis assessment.

Area of Science:

  • Neurology
  • Cardiology
  • Endocrinology

Background:

  • Ischemic stroke characteristics and prognostic features differ between diabetic and non-diabetic patients.
  • Identifying independent predictors of in-hospital mortality in diabetic ischemic stroke patients is crucial.

Purpose of the Study:

  • To compare ischemic stroke characteristics and prognosis in patients with and without diabetes.
  • To determine independent predictors of in-hospital mortality in diabetic ischemic stroke patients.

Main Methods:

  • Prospective stroke registry of 1,840 patients over 12 years.
  • Comparison of demographic data, risk factors, clinical events, stroke subtypes, neuroimaging, and outcomes between diabetic and non-diabetic groups.
  • Multivariate analysis to assess predictors of in-hospital mortality in diabetic patients.

Main Results:

  • Diabetic patients had more atherothrombotic stroke (41.2%) and lacunar infarction (35.1%) than non-diabetic patients.
  • In-hospital mortality rates were similar: 12.5% for diabetic and 14.6% for non-diabetic patients.
  • Independent predictors of ischemic stroke in diabetics included ischemic heart disease, hyperlipidemia, advanced age, and specific stroke types; mortality predictors included age, consciousness level, nephropathy, heart failure, and atrial fibrillation.

Conclusions:

  • Ischemic stroke presents differently in diabetic patients, with a higher prevalence of atherothrombotic and lacunar infarcts.
  • Early clinical factors indicating stroke severity are key predictors of in-hospital mortality.
  • These findings can assist clinicians in more accurate prognosis assessment for diabetic stroke patients.
Abstract

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