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Advances in antiviral therapy.

Jashin J Wu1, Katie R Pang, David B Huang

  • 1Department of Dermatology, University of California at Irvine, 92697-2400, USA.

Dermatologic Clinics
|April 20, 2005
PubMed
Summary

Antiviral therapies treat common herpesvirus infections. Immunomodulating agents like imiquimod combat human papillomaviruses (HPVs) and molluscum contagiosum (MC) by boosting the immune system, reducing disease recurrence.

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Area of Science:

  • Virology
  • Immunology
  • Dermatology

Background:

  • Herpesviruses (HSV-1, HSV-2, VZV, EBV, CMV) are managed with antiviral treatments.
  • Human papillomaviruses (HPVs) present diverse clinical manifestations, including various cancers.
  • Molluscum contagiosum (MC) is a prevalent, benign viral skin infection.

Purpose of the Study:

  • To review current therapeutic strategies for common viral infections.
  • To highlight the role of immunomodulating agents in managing HPV and MC.
  • To discuss the status of vaccine development for viral diseases.

Main Methods:

  • Literature review of antiviral therapies for herpesviruses.
  • Analysis of immunomodulating agent mechanisms (e.g., imiquimod) for HPV and MC.
  • Survey of available and developing vaccines for viral infections.

Main Results:

  • Antiviral therapies are established for several herpesviruses.
  • Immunomodulating agents effectively target HPV and MC by stimulating host immunity.
  • Vaccines exist for some viral diseases, with ongoing development for HSV-2 and HPV.

Conclusions:

  • Diverse viral infections require varied treatment approaches.
  • Immunomodulation offers a promising strategy for managing HPV and MC by leveraging host immune responses.
  • Vaccine development continues to be a critical area for preventing and controlling viral diseases.

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