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Cerebral protection during carotid stenting using flow reversal
Juan C Parodi1, Luis M Ferreira, Gregorio Sicard
1Vascular Surgery Division, Fundación de Lucha Contra las Enfermedades Neurológicas, Montaneses 2325, Ciudad de Buenos Aires C1428AQK, Argentina.
Journal of Vascular Surgery
|April 20, 2005
Summary
Carotid angioplasty with stenting and the Parodi Anti-Emboli System (PAES) demonstrated safety and efficacy in stroke prevention for high-risk patients. This cerebral protection device effectively reduced embolic complications during the procedure.
Area of Science:
- Interventional Neurology
- Vascular Surgery
- Cerebrovascular Disease Management
Background:
- Carotid angioplasty and stenting (CAS) is a stroke prevention strategy for high-risk individuals.
- Embolic complications are a known risk during CAS.
- A cerebral protection device was developed to mitigate embolization.
Purpose of the Study:
- To evaluate the safety and efficacy of CAS using the Parodi Anti-Emboli System (PAES).
- To assess the effectiveness of PAES in preventing cerebral embolization during CAS.
- To determine the perioperative stroke and death rates in patients undergoing CAS with PAES.
Main Methods:
- 100 patients with severe carotid artery stenosis underwent CAS between 1999 and 2002.
- Wallstents were used with selective pre-dilatation.
- The PAES was employed in all procedures, with neurological evaluations pre- and post-procedure.
Main Results:
- The overall perioperative stroke and death rate was 3%.
- Technical success for CAS with PAES placement was 99%.
- Four patients experienced transient neurologic events, with one attributed to postoperative embolization.
Conclusions:
- CAS with the PAES is effective and safe for stroke prevention.
- The PAES shows potential in preventing cerebral embolization during CAS.
- Further research is recommended to validate these findings.