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Updated: Aug 4, 2026

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Quantification of Breast Cancer Cell Invasiveness Using a Three-dimensional (3D) Model
Published on: June 11, 2014
Quantitative three-dimensional microscopy approaches with applications in breast cancer biology including measurement
Stephen Lockett1, Carlos Ortiz de Solorzano, Daniel Baggett
1National Cancer Institute-Frederick/Scientific Applications International Corporation, Frederick, Maryland, USA. slockett@ncifcrf.gov
Journal of Mammary Gland Biology and Neoplasia
|April 20, 2005
Abstract:
Understanding tissue development, tissue homeostasis and what goes wrong in these processes during tumorigenesis, requires knowledge of the kinetics of multiple, molecular pathways in individual cells while cells are in their tissue context. This review outlines progress and future directions necessary in quantitative microscopy for gaining this knowledge, using the mammary gland as a model system.

