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Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials
Published on: August 13, 2019
Clinical case reports of injectable tissue-engineered bone for alveolar augmentation with simultaneous implant
Minoru Ueda1, Yoichi Yamada, Ryotaro Ozawa
1Department of Oral and Maxillofacial Surgery, Nagoya University Graduate School of Medicine, Showa-Ku, Nagoya 466-8550, Japan. mueda@med.nagoya-u.ac.jp
Abstract:
This clinical study was undertaken to evaluate the use of tissue-engineered bone, mesenchymal stem cells, platelet-rich plasma, and beta-tricalcium phosphate as grafting materials for maxillary sinus floor augmentation or onlay plasty with simultaneous implant placement in six patients with 3- to 5-mm alveolar crestal bone height. All 20 implants were clinically stable at second-stage surgery and 12 months postloading. A mean increase in mineralized tissue height of 7.3+/-4.6 mm was evident when comparing the pre- and postsurgical radiographs. Injectable tissue-engineered bone provided stable and predictable results in terms of implant success.
