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Fetal Echocardiography and Pulsed-wave Doppler Ultrasound in a Rabbit Model of Intrauterine Growth Restriction
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Published on: June 29, 2013

Fetal growth restriction associated with measles virus infection during pregnancy

Kosuke Kobayashi1, Makiko Tajima, Satoshi Toishi

  • 1Department of Obstetrics and Gynecology, Asahi General Hospital, Asahi-shi, Chiba, Japan. kosuke@hospital.asahi.chiba.jp

Journal of Perinatal Medicine
|April 22, 2005
PubMed

We report on a 28-week infant with growth restriction starting after 23 weeks' gestation because of measles virus (MV) infection of the mother. Histological findings for the placenta revealed extensive fibrin deposition and necrosis of the villi, and MV antigen was demonstrated in the syncytiotrophoblast by immunostaining. The MV-specific IgM level in the infant was negative, but that of the mother was positive. Therefore, we speculate that growth restriction is not attributed to direct infection with MV, but to placental dysfunction due to a decrease in intravillous blood flow and oxygen supply to the fetus.

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