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Optical Sectioning and Visualization of the Intervertebral Disc from Embryonic Development to Degeneration
Published on: July 8, 2021
[Interrelation of matrix vesicles with spatial distribution of mineral component in fibrous and hyaline cartilages]
Abstract:
Mineral components of the human fibrous and hyaline cartilages were studied by the methods of light, scanning, transmission electron microscopy and cryofractography. The interterritorial matrix of the fibrous cartilage was found to contain not only the local deposits of mineral in matrix vesicles, but also the calcified collagen fibrils and interfibrillar spaces forming the collagen fibers and occupying its major part. In the hyaline cartilage and in the territorial matrix of fibrous cartilage, mineral deposits were located in mineralized conglomerates, the basis of which was formed by matrix vesicles, surrounded by collagen fibrils and interfibrillar space substance. Such conglomerates participate in the formation of calcospherites.
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