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Related Experiment Videos

Enlarging occult fibroadenomas.

J E Meyer1, T H Frenna, M Polger

  • 1Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115.

Radiology
|June 1, 1992
PubMed
Summary
This summary is machine-generated.

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Fibroadenomas, common breast abnormalities, can enlarge between mammograms, particularly in premenopausal women. This interval growth warrants attention in breast cancer screening protocols.

Area of Science:

  • Radiology
  • Oncology
  • Pathology

Background:

  • Fibroadenomas are common benign breast tumors.
  • Mammographic surveillance is standard for breast abnormalities.
  • Interval growth of fibroadenomas can mimic malignancy.

Purpose of the Study:

  • To evaluate the incidence and characteristics of fibroadenoma interval growth.
  • To identify patient factors associated with fibroadenoma interval growth.

Main Methods:

  • Retrospective review of 1,218 preoperative wire-localization breast biopsies.
  • Analysis of fibroadenomas identified between July 1989 and June 1991.
  • Correlation of interval growth with patient menopausal status and hormone use.

Main Results:

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  • 254 (21%) of abnormalities were fibroadenomas.
  • 26 fibroadenomas (10.2% of all fibroadenomas) showed interval growth.
  • Interval growth occurred in 21 premenopausal women and 5 postmenopausal women on oral estrogen.

Conclusions:

  • Fibroadenoma interval growth is a notable phenomenon.
  • Premenopausal status and oral estrogen use may be associated with interval growth.
  • Further investigation into the clinical significance of interval growth is warranted.