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Published on: May 4, 2020
[Is antenatal corticosteroid administration associated with increased acid gastroesophageal reflux in preterm
Iwona Sadowska-Krawczenko1, Mieczyslawa Czerwionka-Szaflarska, Piotr Korbal
1Oddział Noworodków, Wcześniaków i Intensywnej Terapii Noworodka, SPZOZ Wojewódzkiego Szpitala im. J. Biziela, Ujejeskiego 75, Bygdoszcz, Poland. iesadowska@poczta.onet.pl
The Aim Of The Study:
Preliminary assessment of the incidence of acid gastroesophageal reflux in preterm neonates with and without antenatal administration of steroids.
Material And Methods:
Analysis of 96 neonates born before 34 weeks of pregnancy was undertaken. The patients were divided into two groups: I - those who received antenatal corticosteroids n=22; II - those who received no antenatal corticosteroids n=74. All patients had 24-hour pH-metry and basing on the result of this examination we diagnosed or excluded acid gastroesophageal reflux.
Results:
In group I gastroesophageal reflux was diagnosed in 9/22 neonates (40.9%), in group II in 12/72 (16.2%), odds ratio=3.58.
Conclusions:
The frequency of acid gastroesophageal reflux is higher in preterm infants who received antenatal corticosteroids.
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