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Appendiceal US scans: histologic correlation.

R Spear1, M B Kimmey, K Y Wang

  • 1Department of Radiology, University of Washington Medical Center, Seattle 98195.

Radiology
|June 1, 1992
PubMed
Summary
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High-resolution ultrasonography (US) revealed five echo layers in appendiceal tissue. While normal appendices showed distinct layers, appendicitis caused disorganized architecture and increased wall thickness, though US alone may be misleading.

Area of Science:

  • Gastroenterology
  • Medical Imaging
  • Surgical Pathology

Background:

  • Appendicitis diagnosis often relies on clinical presentation and imaging.
  • High-resolution ultrasonography (US) offers detailed visualization of gastrointestinal tract layers.
  • Understanding US appearances of appendiceal tissue is crucial for accurate diagnosis.

Purpose of the Study:

  • To compare in vitro ultrasonography (US) findings of appendiceal specimens with their histologic features.
  • To evaluate the distinct echo layers and wall thickness in normal versus inflamed appendices using US.

Main Methods:

  • High-resolution in vitro ultrasonography (US) was performed on 20 surgical appendiceal specimens.
  • An articulated-arm system and micropositioner ensured precise spatial correlation between US and histology.

Related Experiment Videos

  • Measurements included overall diameter, submucosal layer thickness, and combined wall thickness.

    • Main Results:

    • Five distinct echo layers were consistently observed in appendiceal tissue, similar to other gastrointestinal structures.
    • Normal and inflamed appendices exhibited these layers, but appendicitis led to disorganized and indistinct architecture.
    • Inflamed specimens showed a substantial increase in the combined wall thickness compared to normal appendices.

    Conclusions:

    • Ultrasonography (US) can visualize distinct echo layers in appendiceal tissue.
    • Appendicitis is associated with architectural disorganization and increased wall thickness on US.
    • US appearance of appendiceal wall alone may not be sufficient for differentiating normal from abnormal appendices.