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Updated: Aug 18, 2026

Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients
Published on: December 18, 2016
Epilepsy and variation in the frontal lobe artery
Nobuyuki Maruyama1, Atsushi Fukuma, Ikuo Ihara
1Department of Neurosurgery, Shimane University School of Medicine, 89-1 Enya-cho, Izumo, Shimane 693-8501, Japan. nogeka@med.shimane-u.ac.jp
Abstract:
A patient with a rare variation of fronto-orbital artery (FOA) that developed generalized tonic and clonic seizures is reported. The epilepsy focus was in her left frontal region, where blood was supplied by the contralateral fronto-orbital artery. The region was vulnerable to ischemic changes due to a decrease in blood CO2 gas caused by an increase in endogenous progesterone in the luteal period. The anomaly illustrates an important mechanism of ischemia in epilepsy.
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