Related Experiment Video
Updated: Aug 18, 2026

Bilateral Common Carotid Artery Occlusion as an Adequate Preconditioning Stimulus to Induce Early Ischemic Tolerance to Focal Cerebral Ischemia
Published on: May 9, 2013
Simultaneous carotid endarterectomy and coronary artery bypass surgery in Canada
M D Hill1, F M Shrive, J Kennedy
1Calgary Stroke Program, Department of Clinical Neurosciences, University of Calgary, Alberta, Canada. michael.hill@calgaryhealthregion.ca
Insights
Simultaneous carotid endarterectomy (CEA) with coronary artery bypass grafting (CABG) in Canada showed a 2.67-fold increased risk of stroke and death compared to CABG alone. Further randomized trials are needed to confirm these findings.
Area of Science:
- Cardiovascular Surgery
- Neurology
- Vascular Surgery
Background:
- Patients needing coronary artery bypass grafting (CABG) often have comorbid severe carotid stenosis.
- Simultaneous carotid endarterectomy (CEA) may be offered to these patients.
- The safety and efficacy of combined CEA-CABG require further investigation.
Purpose of the Study:
- To evaluate the stroke and death rates associated with combined CEA-CABG compared to CABG alone.
- To assess the incidence of combined CEA-CABG procedures in Canada.
Main Methods:
- Retrospective analysis of Canadian surgical data.
- Comparison of adjusted stroke and death rates between combined CEA-CABG and CABG alone groups.
Main Results:
- In Canada, 0.51% of CABG procedures involved a simultaneous CEA.
- The adjusted stroke and death rate was 2.67 times higher in the combined CEA-CABG group than in the CABG alone group.
Conclusions:
- Combined CEA-CABG procedures are associated with significantly higher adjusted stroke and death rates.
- Randomized controlled trials are necessary to definitively assess the risks and benefits of simultaneous CEA-CABG.
Abstract:
Stroke neurologists are commonly asked to review patients who require coronary artery bypass grafting (CABG) but who also have comorbid severe carotid stenosis; such patients may be offered simultaneous carotid endarterectomy (CEA). In Canada, 0.51% of CABG procedures were combined CEA-CABG. The adjusted stroke and death rate was 2.67-fold greater in the combined CEA-CABG group compared to CABG alone. Randomized trials of the combined procedure are needed.
Related Concept Videos
Coronary Artery Disease V: Interprofessional Care
Acute Coronary Syndrome IV: Interprofessional Care