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Updated: Aug 18, 2026

Activated Cross-linked Agarose for the Rapid Development of Affinity Chromatography Resins - Antibody Capture as a Case Study
Published on: August 16, 2019
Development and characterization of a new stationary phase for an immunoadsorption wall
1Department of Chemical Engineering, Cheng Shiu University, Kaohsiung, Taiwan, Republic of China. thyang@csu.edu.tw
Abstract:
This study introduces a newly developed method for the formation of a stationary phase superficially embedded with immunoadsorbent, that is partially incomplete two-stage polymerization of acrylamide. Preliminary experimental studies show that binding activity of the immunoadsorbent was satisfactorily maintained after immobilization. With an appropriate configuration of selected immunoadsorption matrices and immunoisolation barriers, it is hoped that this stationary phase could be used to resolve some difficult problems arising from the accumulation of certain middle molecular weight toxins not removed by other blood purification procedures.
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