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Acute renal failure associated with dysfunctioning detrusor muscle in multiple sclerosis
Aslihan Yuruktumen1, Ozgur Karcioglu, Hakan Topacoglu
1Department of Emergency Medicine, Dokuz Eylul University Medical School, Inciralti, 35340 Izmir, Turkey.
Advances in Therapy
|April 29, 2005
Summary
Acute renal failure (ARF) can occur in multiple sclerosis (MS) patients due to bladder dysfunction. Prompt urinary catheterization and treatment led to rapid recovery in this case.
Area of Science:
- Nephrology
- Neurology
- Urology
Background:
- Multiple sclerosis (MS) commonly causes neurogenic lower urinary tract dysfunction.
- Patients often exhibit bladder hyperreflexia and incomplete emptying due to detrusor-sphincter dyssynergia.
Observation:
- A 64-year-old male MS patient presented with decreased urine output and weakness.
- Physical examination revealed a distended bladder and prostate hypertrophy.
- Laboratory results indicated acute renal failure (ARF).
Findings:
- The patient experienced acute urinary outflow obstruction secondary to detrusor dysfunction.
- This obstruction led to ARF, a rare complication in MS.
- Urinary catheterization drained 1100 mL of residual urine.
Implications:
- Acute renal failure is a potential complication of MS-related vesico-sphincter dysfunction.
- Early urinary catheterization and supportive care can facilitate renal recovery in affected patients.
- This case highlights the importance of recognizing urinary issues in MS management.