Related Experiment Video
Updated: Aug 18, 2026

Comparative Lesions Analysis Through a Targeted Sequencing Approach
Published on: November 5, 2019
Acrokeratosis paraneoplastica: Bazex syndrome
M Valdivielso1, I Longo, R Suárez
1Hospital Gregorio Marañón, C/Doctor Esquerdo, 46, 28007 Madrid, Spain. martavaldivielso@aedv.es
Abstract:
Bazex syndrome is a paraneoplastic dermatosis characterized by acral psoriasiform lesions associated with an underlying neoplasm. We present the case of a 64-year-old patient that was diagnosed with squamous cell lung carcinoma after being evaluated for lesions compatible with paraneoplastic acrokeratosis. With a high frequency Bazex syndrome is the earliest marker of an underlying subclinical neoplasm. An early suspicion is of the outmost importance in order to perform a prompt diagnosis of an underlying malignancy. We propose a diagnostic algorithm upon suspicion of acrokeratosis paraneoplastica and review the pathogenesis of this entity.
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