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Related Experiment Videos

Tuberculous mastitis.

Uzma Jalali1, Shahid Rasul, Asadullah Khan

  • 1Department of Surgery, Ward 3, Jinnah Postgraduate Medical Centre, Karachi.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
|April 29, 2005
PubMed
Summary
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Breast tuberculosis commonly presents as a solitary lump or enlarged lymph nodes. Effective treatment involves antituberculous therapy, with surgery reserved for resistant cases.

Area of Science:

  • Infectious Diseases
  • Oncology
  • General Surgery

Background:

  • Breast tuberculosis is a rare, non-specific manifestation of extrapulmonary tuberculosis.
  • Clinical presentation can mimic benign or malignant breast conditions, leading to diagnostic challenges.

Purpose of the Study:

  • To delineate the diverse clinical presentations of breast tuberculosis.
  • To evaluate the treatment outcomes of patients diagnosed with mammary tuberculosis.

Main Methods:

  • An observational study conducted at Jinnah Postgraduate Medical Centre, Karachi, from June 2001 to November 2003.
  • Inclusion of 50 female patients (≥13 years) with clinical signs of breast tuberculosis.
  • Utilized triple assessment (clinical, radiological, histological/cytological) for diagnosis.

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Main Results:

  • Solitary breast lump (60%) and breast lump with axillary lymphadenopathy (26%) were the most frequent presentations.
  • 64% of cases were secondary to tuberculosis elsewhere, primarily tuberculous axillary lymphadenitis (40%).
  • 96% of patients achieved excellent response to one year of antituberculous treatment.

Conclusions:

  • Solitary lumps and enlarged lymph nodes are characteristic of mammary tuberculosis.
  • Prompt diagnosis and antituberculous therapy are crucial for optimal outcomes and preventing breast disfigurement.
  • Antituberculous therapy is the primary treatment; surgery is indicated only for non-responsive cases.