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Updated: Aug 18, 2026

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A Conflict Model of Reward-seeking Behavior in Male Rats
Published on: February 20, 2019
Decrease of kappa-opioid receptor mRNA level in ventral tegmental area of male mice after repeated experience of
Andrey V Goloshchapov1, Maxim L Filipenko, Natalia P Bondar
1Institute of Bioorganic Chemistry SD RAS, Novosibirsk, Russia.
Brain Research. Molecular Brain Research
|April 29, 2005
Abstract:
Brain opioid systems have been implicated in the regulation of social interaction, including agonistic behaviour. kappa-Opioid receptor B and C mRNA levels were decreased in the ventral tegmental area but not in the nucleus accumbens in male mice with repeated experience of social victories (winners), but not in mice after social defeats (losers) after 10 but not 20 days of confrontations. mu-Opioid receptor mRNA levels were not changed.

