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Updated: Feb 8, 2026

A Recovery Cardiopulmonary Bypass Model Without Transfusion or Inotropic Agents in Rats
Published on: March 23, 2018
Transfusion medicine and surgery
1Blood Bank and Clinical Pathology Laboratory, IRCCS Centro di Riferimento Oncologico, Aviano, Italy.
Abstract:
Mortality after surgery in patients with severe and progressive anemia is an entity': risks related to blood loss and insufficient oxygen delivery to tissues are still a major concern in surgery. Risks of blood transfusion parallel those of blood loss: blood-borne infectious diseases and immunological side effects' may frustrate therapeutic efforts of surgery. Thus, blood transfusion in surgery must be kept to a level in which both risks are reduced to a minimum (or theoretically even absent). This review will deal with two relevant questions: (a) how to define the lowest amount of blood tranifusion needed for sur8ery and (b) how to reduce or abolish post-tranifusion risks of this amount.
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