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Updated: Aug 18, 2026

A Hydrogel Construct and Fibrin-based Glue Approach to Deliver Therapeutics in a Murine Myocardial Infarction Model.
Published on: June 14, 2015
Control of suture hole bleeding after aortic valve replacement by application of BioGlue during circulatory arrest
Karin M Dunst1, Herwig Antretter, Johannes Bonatti
1Clinical Department of Cardiac Surgery, Medical University Innsbruck, Innsbruck, Austria.
Abstract:
Bleeding from suture holes in aortic valve replacement (AVR) may represent a difficult problem especially if the aortic wall is friable. We describe a case in which suture hole bleeding after AVR was present at the posterior aortic wall close to the pulmonary artery. Following several attempts to suture the leak using felt pledget armed prolene sutures, deep hypothermic circulatory arrest was induced and BioGlue in combination with Tabotamp was applied for successful sealing of the bleeding source.

