Related Experiment Video
Updated: Aug 18, 2026

Surgical Ablation Assay for Studying Eye Regeneration in Planarians
Published on: April 14, 2017
Recurrent retinal angiomatous proliferation after surgical ablation
Susumu Sakimoto1, Fumi Gomi, Hirokazu Sakaguchi
1Department of Ophthalmology, Osaka University Medical School, 2-2 Yamada-oka, Suita, Osaka 565-0871, Japan.
Purpose:
To report a case of retinal angiomatous proliferation (RAP) treated by ablation of the feeding and draining vessels that recurred by 6 months postoperatively.
Design:
Interventional case report.
Methods:
Images from fluorescein angiography, indocyanine green (ICG) angiography, and optical coherence tomography (OCT) were examined before and after ablation.
Results:
The hot spot on late-phase ICG, the leakage on fluorescein angiography, the pigment epithelial detachment, and macular edema on OCT decreased postoperatively. However, a large hyperfluorescent lesion was detected on ICG 6 months postoperatively with recurrent cystoid macular edema.
Conclusions:
A new RAP lesion can develop even after the original lesion seemed to resolve after ablation.
