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Delirious behavior in children with influenza: its clinical features and EEG findings
Akihisa Okumura1, Takashi Nakano, Yukiko Fukumoto
1Department of Pediatrics, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, Aichi 466-8550, Japan. okumura@med.nagoya-u.ac.jp
Insights
Electroencephalogram (EEG) findings in children with influenza-associated delirium show mild, transient abnormalities. These EEG results may help distinguish delirium from more severe influenza-associated encephalitis or encephalopathy.
Area of Science:
- Pediatric Neurology
- Infectious Diseases
Background:
- Influenza can cause neurological complications in children, including delirium.
- Differentiating influenza-associated delirium from encephalitis/encephalopathy is crucial for appropriate management.
Purpose of the Study:
- To investigate the clinical characteristics and electroencephalogram (EEG) findings in children with influenza-associated delirium.
- To determine if EEG can help differentiate delirium from influenza-associated encephalitis/encephalopathy.
Main Methods:
- A study of 15 children with delirious behavior associated with influenza.
- Clinical courses were reviewed using medical records.
- Electroencephalogram (EEG) was performed during delirious episodes when feasible.
Main Results:
- 13 out of 15 children had a high fever (≥39.0°C) during delirium.
- 10 children showed subtle consciousness reduction, and 5 experienced seizures.
- EEG revealed mild abnormalities in 13 children, including background slowing and slow wave activity, which normalized post-delirium.
Conclusions:
- Electroencephalogram (EEG) findings in influenza-associated delirium are typically transient and mild.
- EEG may serve as a valuable tool in the diagnostic evaluation of children with influenza-associated delirium, aiding in its differentiation from encephalitis/encephalopathy.
Abstract:
The clinical characteristics and electroencephalogram (EEG) findings in delirious behavior in children with influenza were studied in order to differentiate it from influenza-associated encephalitis/encephalopathy. Fifteen consecutive children with delirious behavior associated with influenza were investigated. Their clinical courses were investigated using medical records. EEG was obtained during the delirious behavior, when possible. The body temperature during the delirious behavior was 39.0 degrees C or higher in 13 children. A subtle reduction of consciousness was observed in 10 children. Seizures were observed in five children. EEG revealed some mildly abnormal findings in 13 children, including mild slowing of the background activity, insertion of semirhythmic high voltage slow waves, and appearance of relatively high voltage semirhythmic theta waves. The EEG findings normalized after the delirious behavior had disappeared. EEG revealed transient and mild abnormalities in children with delirious behavior but without encephalitis/encephalopathy, and thus might be useful for diagnostic evaluation in such condition.
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