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Incidentally detected parafalcine chondrosarcoma
M Tosaka1, Y Fukasawa, A Takahashi
1Department of Neurosurgery, Gunma University Graduate School of Medicine, Gunma, Japan. nstosaka@med.gunma-u.ac.jp
Acta Neurochirurgica
|May 3, 2005
Summary
Parafalcine chondrosarcoma, a rare brain tumor, can mimic falx meningioma. Rapid growth and specific SPECT findings can aid in distinguishing this rare tumor from other lesions.
Area of Science:
- Neuro-oncology
- Radiology
- Pathology
Background:
- Parafalcine chondrosarcoma is an exceptionally rare tumor.
- Differentiating it from falx meningioma preoperatively can be challenging.
Observation:
- An 18-year-old woman presented with a parafalcine lesion initially suspected as falx meningioma.
- The lesion showed a ninefold volume increase over two years.
- Brain CT and MRI revealed significant lesion growth.
Findings:
- Single-photon emission computed tomography (SPECT) using thallium-201 chloride ((201)TlCl) and N-isopropyl-p-[(123)I]iodoamphetamine ((123)I-IMP) showed no abnormal uptake.
- Histological examination confirmed a classic low-grade chondrosarcoma.
Implications:
- Rapid growth of a parafalcine lesion warrants consideration of parafalcine chondrosarcoma.
- SPECT imaging with (201)TlCl and (123)I-IMP may help differentiate low-grade chondrosarcoma from meningioma or other tumors in this region.