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Updated: Aug 14, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
A patient with sarcoidosis diagnosed by a biopsy of scleral nodules
Wataru Saito1, Satoshi Kotake, Shigeaki Ohno
1Department of Ophthalmology and Visual Sciences, Hokkaido University Graduate School of Medicine, Sapporo, 060-8638, Japan. wsaito@med.hokudai.ac.jp
Purpose:
To report the case of a patient with nodular scleritis who was diagnosed as having sarcoidosis by a biopsy of scleral nodules.
Methods:
Case report.
Results:
A 26-year-old man with nodular scleritis underwent a biopsy of scleral nodules. The year before, he had been diagnosed with granulomatous iridocyclitis of the right eye. Although sarcoidosis had been suspected, extensive systemic examinations resulted in no positive findings of sarcoidosis. Histopathological specimens revealed non-caseating epithelioid granuloma with giant cells. The nodular scleritis was resolved by topical corticosteroids.
Conclusions:
A scleral biopsy is useful for the diagnosis of sarcoidosis when the patient has nodular scleritis with no systemic signs.

