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Hypopyon uveitis associated with systemic lupus erythematosus and antiphospholipid antibody syndrome
Jeffrey M Zink1, Rita Singh-Parikshak, C Starck Johnson
1Retina Service, Kellogg Eye Center, University of Michigan, 1000 Wall St., Ann Arbor, MI 48105, USA. jzink@med.umich.edu
Purpose:
To report a case of hypopyon uveitis associated with systemic lupus erythematosus and antiphospholipid antibody syndrome.
Methods:
Interventional case report: a 49-year-old woman with a history of systemic lupus erythematosus and antiphospholipid antibody syndrome presented with sudden onset of pain, redness, photophobia, and decreased vision in the left eye. Examination revealed hypopyon uveitis and vaso-occlusive retinopathy.
Results:
Following treatment with intravenous steroids and cyclophosphamide, the patient's vision improved from CF to 20/80 with no inflammation 6 months following initial presentation.
Conclusions:
In this case, systemic lupus and antiphospholipid syndrome were associated with hypopyon uveitis. Prompt treatment with systemic immunosuppressive therapy resulted in improvement in the hypopyon uveitis and vaso-occlusive retinopathy.
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