Single base hits score a home run in wheat
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Development of Targeting Induced Local Lesions IN Genomes (TILLING) Populations in Small Grain Crops by Ethyl Methanesulfonate Mutagenesis
Published on: July 16, 2019
1Department of Agronomy, Purdue University, West Lafayette, IN 47907-1150, USA. cweil@purdue.edu
Abstract:
Finding a way to identify point mutants for a genome in which there are six copies of every gene seems a daunting task, however this has recently been reported. In this research, the redundancy in the wheat genome proved a help instead of a hindrance and the results suggest a promising approach in functional genomics of polyploid crop species. It is now feasible to generate point mutations in all the homologs for a particular gene directly in a polypoid commercial crop variety and then combine them, thus avoiding undesirable, linked traits that often complicate introgressing traits into crops from wild relatives.
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