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Related Experiment Videos

Secondary tics and tourettism.

Nicte I Mejia1, Joseph Jankovic

  • 1Parkinson's Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, Houston, Texas 77030, USA.

Revista Brasileira De Psiquiatria (Sao Paulo, Brazil : 1999)
|May 4, 2005
PubMed
Summary
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Tourette syndrome is a common cause of tics, but other neurological disorders, injuries, and developmental conditions can also lead to tic disorders. Recognizing these associations is crucial for understanding tic physiopathology.

Area of Science:

  • Neurology
  • Movement Disorders

Background:

  • Tics are commonly associated with Tourette syndrome.
  • However, a diverse range of underlying conditions can also manifest as tics.

Purpose of the Study:

  • To investigate the various causes and associated disorders linked to tics beyond Tourette syndrome.
  • To highlight the importance of recognizing these associations for understanding tic physiopathology.

Main Methods:

  • Analysis of data from 155 patients presenting with tics and co-existent disorders.
  • Categorization of tics based on associated conditions, including basal ganglia insults, developmental disorders, genetic conditions, other movement disorders, psychogenic causes, and non-movement neurological disorders.

Main Results:

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  • Basal ganglia insults (head trauma, stroke, encephalitis) were associated with tics in 9.0% of patients.
  • Developmental disorders (Asperger's, mental retardation, autism) were noted in 13.5% of patients.
  • Genetic disorders (Down's syndrome, neuroacanthocytosis, Huntington's disease) were linked to tics in 10.3% of patients.
  • Co-occurrence with dystonia (20.0%) and essential tremor (10.9%) was observed.
  • Psychogenic tics were present in 10.3% of patients.
  • Non-movement neurological disorders like seizures were associated with tics in 7.7% of patients.
  • Conclusions:

    • Tics can arise from or be associated with a wide spectrum of conditions beyond Tourette syndrome.
    • Identifying these diverse etiologies is essential for a comprehensive understanding of tic disorders and their underlying mechanisms.